3,4-Dichloromethylphenidate (also known by the incorrectly abbreviated name 3,4-CTMP) is a synthetic designer stimulant of the substituted phenethylamine and piperidine chemical classes.
It is a structural analog of methylphenidate (commonly known under the trade-name Ritalin). The two substances have very similar pharmacological mechanisms but distinctively different subjective effects. Recently, a study has shown that 3,4-CTMP is a potent agonist of 5-HT2B serotonin receptors.This may partially explain the differing subjective effects in comparison to methylphenidate and raises serious concerns about cardiotoxicity. Other drugs with affinity for 5-HT2B receptors have been linked to extensive valvular heart damage when used chronically, as well as an acute and chronic risk of fatal cardiovascular events due to the induction of pulmonary hypertension.
It is approximately seven times more potent than methylphenidate in animal studies, but likely has weaker reinforcing effects due to its slower onset of action. According to anecdotal reports, the active dose of 3,4-CTMP is approximately 10 times lower than the dose of methylphenidate to achieve a similar effect. 3,4-CTMP has a duration of 6 to 18 hours rather than the 4 to 6 hour duration found with methylphenidate, which can result in regular once-daily usage occurring that may cause dependence on the substance to provide wakefulness, and stimulant effects in a similar manner to dependence on eugeroics, like modafinil and armodafinil, that can occur with regular once-daily usage.
3,4-CTMP has an extremely short history of human recreational use and has yet to be documented being sold on the streets. It is available for sale https://venuschem.com/.
Due to its potent stimulant effects, likely habit-forming properties as well as an unknown, but likely dangerous toxicity profile both in the short and the long term, it is strongly recommended that one use proper harm reduction practices if choosing to experiment with this substance. It is strongly recommended that if one chooses to consume this substance it should be used in low doses and only occasionally. Those with cardiovascular diseases of any kind should not consume this substance. It should also be measured via volumetric dosing, as most scales, including mg scales, lack the accuracy necessary. It is strongly recommended that one not insufflate 3,4-CTMP as it has a low solubility in water so is not readily absorbed through the nasal mucus membrane and anecdotal reports suggest that insufflation of the substance is painful and potentially extremely caustic.Additionally, the poor adsorption by the nasal mucus membrane often results in the majority of the substance slowly entering the stomach through a post-nasal drip, making the onset duration even longer, which may increase the chance of an ‘accidental overdose’ if one redoses more due to a lack of effect.
Phenidate / Piperidine
For anybody interested in the methylphenidate family of chemicals, 3,4-CTMP offers a legal means by which to conduct comparable research into these psychostimulants.
Studies have shown that 3,4-CTMP acts as both a dopamine and norepinephrine reuptake inhibitor, with stimulant effects that are seven times more potent than methylphenidate. It also displays greater reinforcement properties than Cocaine.
Available in a pellet form, BuyAnyChem sells high quality 3,4-CTMP for research purposes only. It is not meant for human consumption.